MovDisordV3, France, Analysis, bibRecord, 000135

A Critique of Available Scales and Presentation of the Non-Human Primate Dyskinesia Rating Scale

Identifieur interne : 000135 ( France/Analysis ); précédent : 000134; suivant : 000136

A Critique of Available Scales and Presentation of the Non-Human Primate Dyskinesia Rating Scale

Auteurs : Susan H. Fox [Canada] ; Tom H. Johnston [Canada] ; QIN LI [République populaire de Chine] ; Jonathan Brotchie [Canada] ; Erwan Bezard [République populaire de Chine, France]

Source :

Movement disorders [ 0885-3185 ] ; 2012.

RBID : Pascal:12-0393073

Descripteurs français

Pascal (Inist)
- Dyskinésie, Maladie de Parkinson, Syndrome choréique, Dystonie, Pathologie du système nerveux, Homme, Primates, Echelle d'évaluation, Lévodopa, Singe.
Wicri :
- topic : Homme, Singe.

English descriptors

KwdEn :
- Chorea, Dyskinesia, Dystonia, Evaluation scale, Human, Levodopa, Monkey, Nervous system diseases, Parkinson disease, Primates.

Abstract

Levodopa-induced dyskinesia (LID) is a major limitation of long-term management of Parkinson's disease. The roadblocks that have hindered the development of new treatments for levodopa-induced dyskinesia were discussed at a meeting organized by the Michael J. Fox Foundation for Parkinson's research (New York, NY, March 2011). Among these, the lack of consensus methodology and clinical applicability for eliciting and rating LID in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated monkeys was highlighted as a particular concern. Here we present an update on the practical use of rating scales for evaluating LID in MPTP-lesioned primate models of PD, with a focus on macaques, and present specifics on the Non-Human Primate Dyskinesia Rating Scale.

Affiliations:

Links toward previous steps (curation, corpus...)

to stream PascalFrancis, to step Corpus: 000082
to stream PascalFrancis, to step Curation: 002C32
to stream PascalFrancis, to step Checkpoint: 000310
to stream Main, to step Merge: 001289
to stream Main, to step Curation: 001237
to stream Main, to step Exploration: 001237
to stream France, to step Extraction: 000135

Links to Exploration step

Pascal:12-0393073

Le document en format XML

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<front><div type="abstract" xml:lang="en">Levodopa-induced dyskinesia (LID) is a major limitation of long-term management of Parkinson's disease. The roadblocks that have hindered the development of new treatments for levodopa-induced dyskinesia were discussed at a meeting organized by the Michael J. Fox Foundation for Parkinson's research (New York, NY, March 2011). Among these, the lack of consensus methodology and clinical applicability for eliciting and rating LID in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated monkeys was highlighted as a particular concern. Here we present an update on the practical use of rating scales for evaluating LID in MPTP-lesioned primate models of PD, with a focus on macaques, and present specifics on the Non-Human Primate Dyskinesia Rating Scale.</div>
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	Movement Disorders (revue)
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Movement Disorders (revue)

A Critique of Available Scales and Presentation of the Non-Human Primate Dyskinesia Rating Scale

A Critique of Available Scales and Presentation of the Non-Human Primate Dyskinesia Rating Scale

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri